Sentence examples for generalized role from inspiring English sources

Exact(17)

Endocannabinoids and cannabinoid CB1 receptors are known to play a generalized role in energy homeostasis.

This YAP driven increase in proliferation occurs in a number of different developing murine tissues, suggesting a generalized role of YAP to promote cellular proliferation in mammalian cells [46, 47].

Its isoforms, which are created by alternative promoters and alternative splicing, have divergent abilities to transactivate p53 reporter genes and induce apoptosis [33] (suggesting a more generalized role).

This data suggests that the GPNMB/OA may play a more generalized role in promoting tumor progression, but does not preclude the possibility that certain GPNMB/OA-related functions specifically favor the development of bone metastases.

Further work is needed to fully understand the subunit composition of BAM holo-complexes, but the evidence so far suggests a generalized role for OmpA-domain proteins in anchoring the BAM complex to the peptidoglycan layer of diverse Gram negative bacteria.

The effectiveness of the LT-IFN pathway against two distinct pathogens suggests a more generalized role in host defense.

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Similar(43)

XCI has served as paradigm for understanding factors with generalized roles in gene silencing genome-wide such as DNA methylation and Polycomb protein-mediated histone methylation [ 1– 3].

The high density of metal-related genes contained within sliGI-1, which seems to have a mosaic structure with elements from both closely and distantly related organisms, strongly hints toward a generalized functional role of this locus in metal homeostasis.

The adjacent ice-binding proteins can be readily detected but are far-less abundant, perhaps pointing to a more generalized and important role for proteorhodopsin.

While the generalized anti-oxidant role might suggest a relatively widespread distribution for PRDX-2 in C. elegans the previously reported expression patterns indicated a more tissue-, even cell-specific localization suggesting that PRDX-2 may play one of these more discrete, specialized functional role(s).

However, these conserved proteins, derived from a single gene, are expressed in numerous tissues indicative of a more generalized housekeeping function in addition to their tissue-specific roles.

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