In a trial of ten patients with severe generalized AD, exposure of one side of the body to high-dose UVA1 and exposure of the contralateral side to half that dose (medium dose UVA1) five times weekly for three weeks, resulted in significant improvement over baseline (29%38%%) which was comparable for both sides.
Nonetheless BPA is widely used in a variety of consumer products leading to a generalized human exposure although its risks remain highly controversial [ 23].
To further evaluate the potential of our cell culture assay and the use of monitoring E1 function as a generalized response of exposure to environmental toxins, we evaluated ub-E1/E1 ratios in samples treated with a series of compounds, including additional dithiocarbamates, thiocarbamates, triazines, benzimadazoles, and several metals (Table 1).
In a prior study, we reported that while causing no generalized histopathology, such exposures could cause hemorrhage in the choroid plexus and lateral ventricles as well as induce shear-related lesions, which may be unique to blast-induced brain injury [ 12].
However, these results were well represented by a gamma-type distribution which is a more realistic and generalized function of the exposure time distribution.
For comparison of the generalized effects of cocaine exposure, the two behavioral classes were pooled and are classified "cocaine-experienced".
The clinical manifestations of TCE exposure include generalized severe dermatitis, fever, abnormal liver function, jaundice, and lymphadenopathy.
In countries of sub-Saharan Africa with generalized HIV epidemics, HIV exposure occurs in up to 25% of pregnancies.
Verschoyle and colleagues (Verschoyle and Aldridge 1980; Verschoyle and Barnes 1972) conducted structure activity relationship studies with a series of pyrethroids and described two generalized syndromes after acute exposure.
