Sentence examples for generalized alignment from inspiring English sources
This includes the classical edit-distance [28] as well as any generalized alignment problem.
Residual dipolar couplings were calculated from the ensemble using a method based on molecular shape, described previously, in combination with a generalized alignment tensor.
Despite this practical advantage over the global and local alignments, the generalized global alignment does not give good results when applied to a pair of sequences whose regions can be partitioned into highly conserved, conserved and unconserved, which is actually what occurs frequently in the real data.
A generalized global alignment (Huang and Chao, 2003) algorithm is generally also unable to solve the formulated problem.
With the practical restrictions of the generalized global alignment, Huang and Brutlag describe in [19] an algorithm that computes an optimal alignment of two sequences by using a set of multiple parameters with different levels of stringency.
Factors that have consistently been reported as associated with radiographic OA progression are obesity, generalized OA, alignment and synovitis.
Unfortunately, there are still situations where even the generalized global alignment cannot be applied in a meaningful way.
The generalized global alignment can be used to distinguish between conserved and unconserved regions of pairs of sequences.
In order to deal specifically with sequences whose conserved regions are intervened by unconserved ones, such as protein and prokaryotic gene sequences, Huang and Chao proposed in [20] the generalized global alignment.
A generalized global alignment algorithm (GAP3) is a development of the standard Needleman-Wunsch dynamic programming algorithm designed for comparing sequences with intermittent similarities, an ordered list of similar regions separated by different regions.
In order to deal with sequences that have intermittent similarities, Huang and Chao proposed in [20] a variant of the global alignment called generalized global alignment.
