Sentence examples for generalized activation of the from inspiring English sources
By consequence, the changes described above are specific to somatosensory cortex, and are not a generalized activation of the ERK1/2 signaling pathway by HU in the whole cortex.
Sepsis is a generalized activation of the immune system in the presence of clinically suspected or culture-proven infection.
Sepsis is the systemic generalized activation of the innate immune response due to infection, involving cellular inflammatory responses triggered by intracellular oxidative stress.
Functional disturbances in EE include reduced absorption, increased turnover of intestinal cells, increased mucosal permeability, and generalized activation of the innate and adaptive immune system (29).
Many, but not all, severe bacterial infections induce thrombocytopenia as a result of DIC, a condition precipitated by the generalized activation of the coagulation cascade in response to bacterial components such as LPS and peptidoglycan[ 34, 35].
Together these findings strongly indicate that the skewed gut microbial communities and the associated "leaky" gut barrier leads to generalized activation of the immune system and drive the expansion of self-reactive B and T cells and production of auto-antibodies.
On the other hand, Figure 3B documents the generalized activation of different circuits of the apoptosis pathway in ob/ob 16 week mice when compared to the 16 week WT mice.
Both infectious (sepsis) and non-infectious insults (trauma) can produce a systemic inflammatory response syndrome (SIRS), characterized by systemic proinflammatory cytokine release and generalized activation of leukocytes and the endothelium, leading to multiple organ dysfunction syndrome (MODS).
The higher sensitivity of these biomarkers in smear-negative HIV+TB+ patients is likely related both to a greater in vivo bacterial burden as well as the generalized activation of B cell responses, including the antigen-specific B cells, caused by HIV-infection [37], [38], [39].
Second, total body irradiation as well as the absence of Tregs may result in the generalized activation of APCs [15], [16].
Possibly, in patients, the BIS-1 F(ab′)2inducedn induced lymphopenia is a result of generalized activation of endothelial cells, leading to the formation of a temporary sink for lymphocytes.
