Nine nurses and seven doctors were interviewed and several of them suffered symptoms of having been exposed to sarin, "with one describing the onset of blurred vision, generalised weakness, shaking, a sensation of impending doom, followed by fainting".
Constitutional symptoms were defined as one or more of tiredness, generalised weakness, anorexia or reported weight loss.
Seven weeks after starting chemotherapy he was admitted with a 10-day history of progressive confusion, drowsiness, generalised weakness, and fatigue preventing him from walking.
Generalised weakness with marked hyperkalaemia and dehydration has been reported as the first presentation in a middle-aged man after concurrent institution of indapamide for hypertension and bowel preparation for barium enema.
At emergency department presentation, a history of dyspnoea, increased/purulent sputum, irritability, and wheezing were all significantly more common in cases than in controls, whereas diarrhoea, nausea/vomiting, generalised weakness, syncope/dizziness, myalgia, and chest pain were not.
Other studies suggest that the presence of certain symptoms such as headache, dizziness, loss of consciousness, memory loss, blurred vision, generalised weakness, pain in limbs and seizures make the diagnosis of TIA less likely.
They become increasingly easily fatigued, loose muscle mass and have generalised muscle weakness as well as lower exercise tolerance [ 13, 16].
In an unselected population of critically ill children, the occurrence of generalised muscle weakness was substantially lower (1.7%), reflecting the need for future studies to include much larger samples of unselected ICU patients to evaluate the true incidence of ICU-acquired neuromuscular disorders.
34 35 ICU survivors frequently suffer from profound weakness, generalised muscle wasting, impaired mobility and weight loss on transfer to the general ward, a situation described as 'inexplicable and worrying' 36 and a 'critical defining characteristic' of the distress survivors experience at this time.
Young adults present with progressive weakness and generalised muscle atrophy.
We report the case of a 34-year-old man who presented with a one-month history of lethargy, generalised upper and lower limb weakness and significant weight gain.
