Given that a relatively low proportion of MSI in Rwanda is attributable to the genocide, this means that it may be possible to generalise the prevalence and causes of MSI in Rwanda to other similar African settings for which data are lacking.
Therefore, it may be incorrect to generalise male prevalence to females.
While there might be an argument for generalising these prevalence estimates to the UK, we need to be more cautious in making the same case for the reliability estimates.
As such, while the sample was randomly drawn, it is unlikely to be representative of the general population and thus caution should be used when interpreting and generalising absolute prevalence estimates.
To compare different reliability coefficients (exact agreement, and variations of the kappa (generalised, Cohen's and Prevalence Adjusted and Biased Adjusted (PABAK))) for four physiotherapists conducting visual assessments of scapulae.
In European countries, the lifetime prevalence of generalised anxiety disorder (GAD) varies from 5to10%0% [ 1- 5].
Unlike geographically determined disease such as Chagas disease and Guinea worm infections cited by Reidpath and Allotey, HIV is found in every nation and the epidemic in many populous countries is becoming generalised (> 1% prevalence).
Random effects meta-analyses were used to calculate the lifetime prevalence of comorbid generalised anxiety disorder, panic disorder, social anxiety disorder, specific phobia, agoraphobia, obsessive compulsive disorder and posttraumatic stress disorder in bipolar affective disorder.
3 4 Yet, the modest size of these studies (100 and 200 patients) and the populations they describe (a clinic-based cohort, and a community-based cohort with overall mild disease course 5) allows for the possibility that their prevalence estimates might not generalise to the wider MS population.
However, the study is not representative and the prevalence figures cannot be generalised across populations.
