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In general, linkage disequilibrium (LD) in a population can be generated by selection, genetic drift, or population structure, and it is eroded by recombination.
The compound noun hook-up (which The Times no longer hyphenates) was born in a political context in 1903, as "a hook-up with the reform bunch," and meant a general linkage.
It highlighted not only a more general linkage between immigrant integration and immigrant selection, but also a double conditionality imposed in this policy area – where both the civic deservingness of the sponsor and the civic integration potential of the incoming family member were evaluated.
These results further support the notion that first exonic methylation is linked to transcriptional silencing and argues against a general linkage between composite gene body methylation and transcription.
No general linkage disequilibrium was observed for any locus (all p > 0.05 after Bonferoni correction).
In these haloarchaeal genomes, the bR gene was observed in three general linkage states.
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The influence of key parameters on the performance of this model is investigated through numerous dynamics simulations with a general linkage-mechanism.
In general, record linkage is the process that determines which entries in a set of personal records belong to one person.
In general, the linkage rate decreased with increasing age at diagnosis, and we thus performed analyses stratified by year of birth (all, birth year > 1930 and birth year > 1950).
This theory may be seen as a special case of a more general theory for linkage based on preservation of linkage disequilibrium under epistasis [ 27- 30].
Similarly, the impacts of migration and remittances may extend beyond the migrant-source household, as a result of a variety of local general-equilibrium linkages.
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