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The results that we present have general implications for our understanding of the thermodynamic properties of repeat proteins.
Our study reveals a function of spectrin as a mechanoresponsive protein and has general implications for understanding spectrin function in dynamic cellular processes.
How is that possible, and if true, what are the general implications for our understanding of the basic scientific principles we live by now?
Our analysis and results have general implications for designing programs aimed at preventing fraud and for fraud risk assessment within the audit context.
In addition, re-evaluations of the volcanic features in SW Idaho have some general implications for the usage of phreatomagmatic pyroclastic rocks for paleoenvironmental reconstruction.
These findings could have general implications for Alzheimer's disease pathogenesis and particular relevance to patients heterozygous for the Arctic APP mutation.
This work has general implications for river ecosystem management in water-stressed basins, particularly in terms of the design of fair and effective water sharing mechanisms.
We discuss the outcomes of the planning protocol in terms of site prioritisation, stakeholders' participation and general implications for spatial planning in insular systems.
These findings explain why apparently inconsistent structure-activity relationships (SARs) can coexist in different targets, and they have general implications for compound screening and optimization.
The paper discusses the impact of the approach and suggests general implications for the way in which policy analysis is conducted.
Thus, we report an approach for the molecular evolution and selection of broadly crossreactive antibodies towards a family of structurally related, yet sequence-diverse protein targets, with general implications for the development of novel therapeutics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com