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A general depletion of let-7 during development generates more dramatic effects in males.
"Considering the general depletion cited in this boy's history, pica seems like a real contender".
The ever-increasing demand for Picos has led to overharvesting and the general depletion of stock.
In the Fs oil sample, there is a general depletion of the n-alkanes up to C13 (Fig. 3).
In the DLB, a general depletion of already scarce water resources affects the general well-being of all population groups, and all aspects of human activity.
A general depletion of B cells by a CD20-specific monoclonal IgG1 antibody has recently been validated as an effective strategy for treating rheumatoid arthritis.
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These findings point to a general severe depletion of top predators in the basin, including Atlantic bluefin tuna, which is considered critically endangered according to the declining trend observed in the Atlantic and the Mediterranean in the last 50 years.
Consistent with previous reports of a role for CK2 in PML turnover [10], CK2 silencing resulted in increased levels of PML-NBs in general, however depletion of CK2 had no noticeable effect on the ability of USP7 or C223S to disrupt PML-NBs (Figure 5A).
In addition, Noxa levels affected the apoptotic response to general nutrient depletion (i.e. amino acids, vitamins).
In the theophylline spike experiments, we hypothesize that the presence of unbound aptamer-AS-2 that builds up in concentration during the prespike reaction competes with AS-1 for RNA degradation machinery, or causes general resource depletion effects, which slows overall reaction rates.
In general, the depletion of the soluble transition metal M in Pt x M alloys with low M concentration (x > 1) in acidic pH environment is limited to the surface region, resulting in thin Pt-rich shell and solid M-rich core structures.
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