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To do so, they added back a small amount of the NOE and RDC data, but just in the parts of the analysis that deduce the shape of the general backbone of the protein rather then the position of all the individual atoms in each amino acid side chain.
The general backbone detection problem is thus how to find a smooth mid-axis through the set of scattered worm nuclei.
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In general, the backbone amides with large 15N-{1H}-NOE values (0.7 1.0) are expected to have lower flexibilities and to be located in the rigid region, while those with small NOE values (<0.6) are considered to be located at the loops or linker regions that have high flexibility [30].
In general, the backbone and side-chain (Arg, Tyr) vibrational modes correlated with the N-H and N-D deformation modes.
Both Weintraub, the author of several books on war, and Perry, who has written on the Joint Chiefs of Staff, the C.I.A. and the Civil War, offer many examples of how even the domineering Franklin Roosevelt could not bend General Marshall's backbone — though not for lack of trying.
Or Offer, CEO, was visibly uncomfortable every time I tried prying details about their technology, but finally relented with some general explanations: The backbone of SimilarWeb's technology is based on multiphase analysis, which in plain English means that there are several engines running in the background, analyzing websites based on different mechanics, metrics and workflows.
Phylogenetic biogeographic methods such as PACT and modified BPA depart from this standard approach in that in addition to searching for a general area cladogram, the "backbone" of the tree, which is interpreted as resulting from vicariance or geodispersal events, they attempt to infer other processes that are lineage-specific.
STIL-CC binding leads to an increase in averaged heteronuclear NOEs for β-strands and the α1 helix, suggesting a general reduction of fast backbone motions of PLK4-PB3 upon STIL-CC binding.
Invisible as it might be to the general public, it remains the backbone of American soccer.
From less directional, early encounter conformations a general ordering transition with increased backbone hydrogen bond interactions was observed.
Besides group iii), which specifically interacts with the phosphonate group of alafosfalin, the other three groups represent the general recognition mode of the backbone of dipeptides.
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CEO of Professional Science Editing for Scientists @ prosciediting.com