Sentence examples for gene substitute from inspiring English sources

Transgenic mutant (TGmut) mice express the mutant PRKAG2 gene (substitute of arginine for glutamine at residue 302), with transgenic wildtype (TGwt) mice expressing the normal human PRKAG2 complementary deoxyribonucleic acid (cDNA).

Wt and the recombinant viruses contain the GFP gene substituted for the dispensable, 10-kb US1 US12 region (US, unique short).

Cells were plated on 5-FOA where viability requires that the human gene substitutes for its yeast ortholog.

The yellow color of carotenoid was observed in the transformant, indicating that pGGPPS carried the gene substituting the function of the crtE gene (Fig. 4).

We scanned the entire RIF2 gene substituting every six codons with the sequence specifying the amino acid sequence asparagine-alanine-alanine-isoleucine-arginine-serine (NAAIRS) in continuous blocks.

Curiously, three of the lymphomas showed a similar spectrum of genetic defects involving unusual heterozygous deletions of a region around amino acids 140-148 of the p53 gene, as well as identical, in-frame deletion/insertions in the Bub1 gene substituting M290 with codons encoding isoleucine and arginine.

If a new virulent influenza strain emerges in the population, he says, "we can isolate the [underlying] genes, substitute them in current vaccine strains, and almost immediately we can produce the new vaccine".

So far, the homologous genes to FLC have still not been found in rice; and it remains unknown whether other genes substitute for FLC in rice.

K27M mutations in both genes substitute a key lysine residue on the histone H3 tail for a methionine, and have been shown to exert biochemical inhibition of the Polycomb Repressor Complex 2 (Presultinglting in a global loss of trimethylation of lysine 27 on all histones H3 molecules either wild types or mutated [ 34].

In the second approach, each gene set from MSigDB that shared genes with the core gene set had the shared genes substituted with random genes that were not already present in the gene set.

The site-directed mutagenesis was performed using human DSS1 gene to substitute the highly conserved amino acid residues.