Sentence examples for gene screen from inspiring English sources

With an aim to elucidate pathways involved in the coordinate control of SREBP signaling and cholesterol homeostasis we analyzed primary results from the gene by gene screen using a Gene Set Enrichment Analysis approach.

Results from the primary gene-by gene screen were analyzed by a novel application of the Gene Set Enrichment Analysis (GSEA) technique modified for high throughput screening data (for details see Materials and Methods).

To understand the pathobiology of these disorders we must first unravel the cell biology of normal bladder development and we therefore undertook a comprehensive gene screen using the mouse as a model.

To gain further insights into how these microenvironments are regulated in vivo, we performed a candidate gene screen designed to identify factors that restrict BMP signal production to the cap cells that comprise the germline stem cell (GSC) niche of Drosophila ovaries.

To identify other histone chaperones that might function in heterochromatin silencing, we performed a small-scale candidate gene screen using a GFP-based reporter gene silencing assay (Fig. 1A).

The 150 gene screen conducted here is too small to extrapolate to an entire genome proper, but the core observations that some phenotypes are only detectable after the use of non-visible assays suggests that current 2000 gene numbers[14] are likely underestimates.

All of these are advantageous for cell-based gene screening.

Fujinami, K. et al. ABCA4 gene screening by next-generation sequencing in a British cohort.

However, a practical gene screening strategy for identifying such factors has not yet been developed.

Target gene screening: We further explored the possible mechanism involved in the osteogenesis of gene-modified PDLSCs.

Phenotype Based Functional Gene Screening Using Retrovirus-Mediated Gene Trapping in Quasi-Haploid RAW 264.7 Cells / Soon-Duck Ha -- 24.