The DIAPH1 gene resides at 5q31.3, between the two most oft-cited CDRs, and encodes the formin mDia1.
If a haplotype map of the human genome could be constructed, then the genomes of patients and control groups could be compared block by block, helping to identify the block in which a disease-causing gene resides.
The hepatitis B virus (HBV) pre-X gene resides upstream of the HBV X gene, and together they form the HBV whole-X gene.
Once linkage mapping has determined the area in which a disease gene resides, tracking SNPs is already used to help locate the exact culprit.
Markers mapped this QTL to an introgressed chromosome segment at the lower end of A03 (Aradu.A03, 131,305,113 133,690,542) where an NB-LRR encoding geNB-LRR encoding. duranensis (Aradu.Z87JB).
Objective: To investigate a possible association between the carrier frequency of the N314D mutation in the galactose-1-phosphate uridyl transferase (GALT) gene and endometriosis and linkage to the short arm of chromosome 9, where the GALT gene resides.
The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2.
This is a laborious process, taking years just to get a rough idea of where a gene resides.
Equally intriguing, the p73 gene resides in a region of chromosome 1, thought to harbor multiple unidentified tumor suppressor genes.
Earlier research identified the chromosomal neighborhood where another prostate cancer gene resides, but so far the gene hasn't been pinpointed (ScienceNOW, 21 November 1996).
The Bph13 gene resides in the region flanked by RG100 and RG 191 region (Renganayaki et al. 2002), while the bph19 gene was mapped in the region flanked by RM517 and RM218 (Chen et al. 2006).
