Sentence examples for gene render from inspiring English sources

However, mutations in the KRAS gene render the KRAS protein constitutively active regardless of extracellular EGFR inhibition[ 2].

Coding or splice site mutations in the LEP gene render the leptin protein unable to signal through its receptor, which leads to severe childhood-onset obesity.

The recognition that activating mutations in the KRAS gene render patients non-responsive to therapy with anti-EGFR monoclonal antibodies has resulted in the need for tumour mutation status to be ascertained before treatment.

The MoFLP1 gene is a member of the fasciclin family and predicted to be involved in cell adhesion; null mutants in this gene render the fungus less adhesive and less pathogenic [ 48].

Callaway and his team began with a vaccine form of the rabies virus that was missing the hook-making gene, rendering it unable to jump between cells.

This made the resulting protein resistant to the venom, whereas substituting the pore DNA sequence in the grasshopper gene with that from the common mouse gene rendered it highly sensitive to the venom.

Both P. chrysogenum and P. notatum contain pahA, but a single base pair change in P. chrysogenum 's gene renders the enzyme less active.

Transduction of 293T cells with the IN-defective lentiviral-hybrid episomal vector containing the thymidine kinase (TK) gene rendered the Tag expressing cells highly susceptible to ganciclovir (GCV) treatment, as opposed to the cells infected with the control vector or in Tag negative cells.

The third dish at time 0 contains the same bacterial strain as the second dish, but soon after (time denoted by green arrow), a subpopulation experiences a rare beneficial mutation in a cell membrane glucose transport gene, rendering it a more efficient glucose transporter compared with the original strain.

Replacement of the HyTK target with the μ reporter gene renders the cells gancyclovir-resistant (ganR).

First we examined the survival of S. aureus strain 8325-4 in which an 11bp deletion in the rsbU gene renders the sigB operon essentially non-functional [60].