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Pseudogenization of the ancestral copy constitutes gene relocation.
The example we report is the first characterization of functional gene relocation within a euchromatic LCR.
Thus, changes in expression and function are considered to be another consequence of gene relocation.
This suggests that gene relocation is not driven by spermatogenic X-inactivation.
Here we present a novel example showing functional gene relocation within a LCR.
The gene relocation by polyplexes and lipoplexes is less efficient in vivo than in vitro.
Similar(37)
These alterations are often accompanied by gene relocations in relation to other genomic regions or to nuclear compartments.
Gene relocations have been described previously in S. cerevisiae where the DAL gene cluster, including six genes, was formed by gene relocations from six different loci [ 42].
In this study, the frequent gene relocations identified in non-conserved regions of F. graminearum drove us to hypothesize that the generation of LS chromosomes in F. oxysporum could also have included extensive gene relocations.
In this study, many gene relocations were identified in non-conserved regions of F. graminearum, in contrast to conserved regions.
This result suggests that secondary metabolite gene clusters could be formed by gene relocations as was found for other genes in the non-conserved regions.
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