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Gene reassignment between modules is often consistent with changes in lifestyle or the copy number of chromosomes.
Mitochondrial tRNA gene reassignment has been reported in some invertebrates (e.g., [ 55]) but, to the best of our knowledge, it is uncommon in vertebrates.
In addition, the T. tripolitanus mitogenome may have gone through tRNA gene reassignment from tRNAArg to tRNAGln by a point mutation at the second anticodon position, although the novel tRNAGln gene may not be fully functional in translation.
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Subsequently, she had gender reassignment surgery.
Duplicates are more likely to be reassigned than single-copy genes, with this reassignment often occurring in a brief 'window of opportunity' after duplication; however, duplicates that arise from the whole-genome duplication continue to be reassigned over a much longer time.
We assessed the contribution of gene duplication to module reassignment at several levels.
To assess the tendency of a gene to be reassigned between modules before and after duplication, we compared the normalized number of reassignments of a gene pre-duplication to the minimum, maximum and average of the normalized number of reassignments of its two 'descendant' copies post-duplication.
(C ) Cumulative distribution of module reassignment of genes before and after their duplication.
Third, we analyzed the reassignment of genes at each phylogenetic point.
(D ) Scatter plots showing for each gene its degree of module reassignment before duplication (x axis) vs the average degree of module reassignment of the two paralogs after duplication (y axis).
We would suggest that stop-to-sense codon reassignment corresponds with decreasing gene number, but increasing gene length.
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