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Our finding is compatible with the expression pattern and target gene preference of the HIF-2 α subunit.
Third, when multiple probe sets mapped to the same gene, preference was given to "at" probe sets over "s_at" probe sets.
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Although the two complexes often show different gene preferences, they often regulate the same cellular processes.
These facts strongly suggest that the function of these genes may be significantly determined by other characteristics in addition to differences in expression patterns and target gene preferences.
Primers were developed in conserved regions of the genes to avoid gene-specific preference during the amplification process.
As to whether there is a gene length preference for deaminases, for AID* and sA3G* datasets, we find no particular bias for mutations to occur at short or long RNAP II mRNA genes (see Author response image 1 below).
Quantitative real-time PCR (qRT-PCR) analysis was used to verify the relative expression of select genes, with preference given to either known HNF4α targets [21], or genes that contained promoters previously indicated in the literature to bind HNF4α in human cells [22], [62].
The law governing fertility treatment is now being updated in a bill before Parliament, and using PGD to pick embryos with faulty genes in preference to those without them is to become illegal.
For this group of genes, the preference for expression of only one of the alleles is statistically significant (P<0.001).
Understanding how the polymorphism of this receptor gene affects preferences is important to understanding usage of NNS.
To do this, we designed primers to the putative terminal exons of the novel genes, without preference to the abundance of the isoforms that contained these exons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com