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Gene prediction with Prodigal, a prokaryotic gene predicting program, completely supports the new genomic coordinates calculated using proteogenomic mapping.
Twelve deletions (22%) overlap part of SPAST and a portion of a nearby, directly oriented gene, predicting novel chimeric genes in these subjects' genomes.
We searched for the A-PRO domain in the D. discoideum genome, and found a single intronless gene predicting a protein of 423 amino acids (DDB_G0285069).
The third cluster chosen for further phenotypic analysis (Figure 3C) carries a gene predicting a protein with putative phospholipase D activity (BPSS1381), neighbouring an endonuclease/exonuclease/phosphatase family protein (BPSS1382).
All DMD patients had a molecular genetic detection of a mutation in the dystrophin gene predicting a marked dystrophin-deficiency.
For an unknown gene, predicting its functions will assign some GO functional terms to it, which is called multi-label classification problem in machine learning community.
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HPP aims to reach a detailed understanding of the ~20,000 human protein-coding gene predicted from the human genome.
Finally, a SNP in the CLOCK gene predicts delayed sleep timing and reduced sleep duration [26].
Polymorphisms in the INS gene predicted development of T1D.
The Arabidopsis genome contains two copies of genes predicted to encode plastid-localized 6PGDH enzymes and one gene predicted to encode a cytosolic 6PGDH.
Only one predicted CESA-like gene (predicted ortholog of CSLG3) was downregulated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com