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However, the length of the lacZ gene poses challenges for sequence analysis of mutants.
The enormous size of the full-length dystrophin gene poses one of the biggest challenges for gene therapy because it exceeds the packaging limit of most viral vectors.
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But the H.I.V. resistance gene posed an even greater puzzle, said Dr. Stephen J. O'Brien, who is chief of the Laboratory of Genomic Diversity at the cancer institute.
One in three cases of DMD present with no prior family history, 3 and this fact, coupled with the size and complexity of the gene pose great challenges to prevention and genetic counseling programs.
The transcriptional memory of Hox genes poses both an opportunity and a challenge for regenerative medicine.
The rise of antibiotic-resistant genes poses a potential worldwide human health risk.
The extraordinarily high level of genetic variation of HIV-1 env genes poses a challenge to obtain antibodies that cross-react with multiple subtype Env glycoproteins.
It is well known that AT richness and repeat structure of var genes poses large difficulties in the assembly of short sequence reads.
The overlap of MAE and bivalent genes poses a potential mechanistic puzzle.
The truncation of these genes poses problems in locating and annotating the tRNA genes (Masta and Boore 2004).
However, the new information that we provide here showing an early evolution of Group IIb genes poses a new question.
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