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Gene ordering for purposes of assigning to segments or determining gene adjacency was based on the annotated gene transcription start coordinates.
With respect to biological function, gene expression patterns and the role of genomic duplication, it is unclear how to interpret the significance of the similar human and mouse gene ordering and the variation in gene count between mammals.
The gene ordering in human (chr 19q13) and mouse (chr 7A3) is nearly identical and has been described [18], where the nomenclature has been established as follows: interferon-lamba-1, interferon-lamba-2, interferon-lamba-3 and interferon-lamba-4-pseudo, with the first pair on the reverse strand, and the second pair on the forward strand.
In total, our gene ordering included 14517 genes.
In the second part of the experiments, we evaluate the accuracy of gene ordering through three different setups.
Approaches such as whole genome alignment [ 49] and gene ordering analysis [ 50] construct phylogenetic trees from a genomic point of view.
Similar(35)
Genes ordered by decreasing ratio of FGF PDGF expression.
In the present study gene-pair relationships were examined between the genes ordered in the fosmids and the known gene order in Arabidopsis.
A novel gene order in higher vertebrates.
The evolutionary dynamics of eukaryotic gene order.
Some experts believe gene order can affect pathogenicity.
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