Sentence examples for gene order alignment from inspiring English sources

We propose a method, called CYNTENATOR, to discover conserved syntenic regions over large evolutionary distances by progressive multiple gene order alignment.

We have developed CYNTENATOR, a progressive gene order alignment software, to identify genomic regions of conserved synteny over a large set of diverging species.

Each gene order alignment defines conserved syntenic regions over at least two or more species (CSMs = conserved synteny over multiple species).

We have used the 17-way multiple gene order alignment to define conserved syntenic regions over multiple species (CSMs) and complementary evolutionary breakpoint regions (EBRs).

A simulated block was counted as recovered, if all genes in the block are also found in a single gene order alignment or identified gene cluster.

In a multiple gene order alignment of 9 mammalian species and the platypus genome, 480 (56%) of the 859 RSBs are confined by a gene which is located at one end of a contig.

In short, RSBs are non-redundant, maximal representatives for a set of multiple gene order alignments.

We used EnsEMBL database annotations (release 50) for 17 high-coverage genomes to construct multiple gene order alignments.

Our new software, CYNTENATOR, computes multiple gene order alignments progressively in a bottom-up approach along a given phylogeny.

We have previously shown that gene ortholog assignments, as predicted by the EnsEMBL pipeline, are almost fully recovered by our gene order alignments [20].

We evaluated the effect of parameter choice on ortholog recovery by computing human-zebrafish gene order alignments using various (mismatch × gap) -penalty combination and apart from that default parameters.