Sentence examples for gene mutation assay from inspiring English sources

The mouse lymphoma assay (MLA) is the most widely used in vitro mammalian gene mutation assay.

This set includes a bacterial reverse mutation assay, an in vitro cytogenetic test with mammalian cell culture, an in vitro gene mutation assay in mammalian cell cultures, and an in vivo rodent bone marrow micronucleus test.

These results are consistent with a parallel hprt gene mutation assay.

We therefore tested BrdU with the thymidine kinase (TK) gene mutation assay, a classical assay used to evaluate cytotoxicity and genotoxicity of developing drugs.

An important component of the validation of the Pig-a assay is the comparison of the responsiveness of the mutant Pig-a phenotype endpoint to that of a well-established in vivo gene mutation assay.

In this study we compared the response of the Pig-a gene mutation assay to that of the lacZ transgenic rodent mutation assay, and demonstrated that multiple endpoints can be measured in a 28-day repeat dose study.

A panel of 21 p53 gene mutation assays (MAP or Bi-PAP-A) may detect the mutational signature in ∼30% of breast cancers, based on an examination of data from the IARC TP53 database (www-p53.iarc.fr).

The efficiency and specificity of these inhibitors was demonstrated in gene mutation assays using SULT- and CYP2E1-dependent reference mutagens, 2-nitropropane and N-nitrosodimethylamine, respectively.

Pieces of the liver were frozen for later analysis by gene mutation assays.

A survey of the recent, significant developments on nanomaterials enabled ultrasensitive DNA and gene mutation assays is presented.

In vitro gene mutation assays are generally carried out with continuously dividing cells, despite their distinct metabolic insufficiency.