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It carries a point mutation in exon 23 of the mouse dystrophin gene introducing a premature stop codon, which leads to the loss of full-length dystrophin [ 8].
The mdx mouse model for DMD has a spontaneous mutation in exon 23 of the Dmd gene, introducing a premature stopcodon[ 15, 16].
A single mutation was obtained during the second period of CSI and this affected a putative MFS transporter (Pc22g08250) encoding gene introducing a tyrosine to asparagine substitution at position 304.
While effective, such approaches require a homology construct and zinc finger nuclease that is specific to each target gene, introducing an element of complexity and ruling out large-scale screening approaches.
This unusual phenotype mapped to a single nucleotide change (T to G) in exon 5 of the mechanistic target of rapamycin (Mtor) gene, introducing serine in place of isoleucine at position 205 in the fifth predicted HEAT domain of the protein (Knutson, 2010).
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But no single gene introduced alone was able to manage the transformation.
It was concluded that the gcsgs gene introduced into Enterobacter sp. CBSB1 upgraded the phytoremediation efficacy of B. juncea.
As shown in (Figure 2), codA does not exist in NT, while the exogenous codA gene introduced into transgenic SC plants could be observed.
The results are consistent with the results of previously studies on the sd1 gene introduced in other varieties (Hedden [2003]; Luo and Yin [2013]; Spielmeyer et al. [2002]).
Longer gene introduces more noise, which tends to reduce power.
Of central importance for our analysis is the notion of the causal membership of a gene introduced in [19].
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