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These data show that many of the proteins we identify in vivo as upregulated in highly metastatic tumors show corroborative evidence – from other papers and/or from our comparisons with gene expression metadata analyses – supporting their roles in human breast cancer.
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Each file (n = 2,869) was parsed using a Perl script to extract gene expression matrix and metadata.
This database contains fully annotated clinical metadata and gene expression patterns generated within 12 controlled studies across 6 different microarray platforms.
Similar to its predecessor, PROGgeneV2 is written in PHP5 with a MySQL database backend which stores gene expression data, covariates data and metadata for catalogued studies in form of relational database tables.
Sample metadata and normalized gene expression data was submitted to NCBI's Gene Expression Omnibus (GEO; entry GSE53907).
FFGED features user-friendly management of gene expression data, which are assorted into experimental metadata, experimental design, raw data, normalized details, and analysis results.
The underlying metadata information for any gene expression study has been underrepresented and thus is largely under-utilized.
Overall, for the prioritization and metadata curation of AD gene expression studies, we spent about 1 year of four biocurators effort (working 10 h/week).
Curated metadata for Alzheimer's disease gene expression studies are available for download.
In order for the gene expression data to be provided in context, additional metadata pertaining to the in situ experiments is also included in the database.
Knowledge-driven approaches are based on the metadata used to describe the deposited gene expression studies.
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