Sentence examples for gene errors from inspiring English sources
We had just decoded the first human genome, and scientists still spent their time searching for very specific gene errors that cause quite serious inherited problems, like muscular dystrophy.
This was found to lead to inconsistencies between the abilities of different curators to find and correct gene errors and new evidence for a gene change would have to wait until the gene was revisited.
Additionally, a systematic analysis to identify possible gene errors of the type we describe here identified interrupted genes in other complete genomes from Gram-negative γ-proteobacteria, and in some of those cases the interrupted genes are orthologs of essential genes in E. coli [ 8, 26].
Such ORFs could be the result of additional sequences in the target genome, minor sequence differences in the reference genome resulting in the loss of a functional gene, errors in the original annotation, overlapping ORFs, or failure to use the first MET codon as the ORF start.
The notion is that targeted medicines could help the small subset of Parkinson's patients with a particular gene error, which 23andMe can easily find in its database.
Huang had only carried out a lab experiment, in which he'd tried to fix a gene error that causes a blood disease.
After discovering the unusual gene error causing the six-year-old girl's problem, researcher Timothy Yu of Boston Children's Hospital believed he could create a treatment tailored to repair it.
In the case of the MYBPC3 gene error, known as an autosomal dominant disorder, half a couple's embryos would be carriers of the disease, but half would not.
From Figure 4A the average ratio for the seven validation genes were extracted and replotted in Figure 4C, which also illustrates the standard deviation of each gene (error bars).
GeneSpring's cross gene error model, which determines the likelihood of observing a specific fold change to the likelihood of observing a fold change of 1, was active during this test.
Unreliable genes were also discarded using the cross gene error model [ 61].
