Exact(1)
Since the launch of the field in 2000 [1],[2], a wide range of synthetic gene devices have been created, including switches [3]-[9], oscillators [10]-[13] [10]-[13]lememory[7],[14],[15], and communication modulelements[7]]-[18], andwell as other elecommunicationired genetic devices, such as digital logic gates [19]-[22], pulse generators [23], and filters [24],[25].
Similar(59)
Image-guided interventions provide the means to deliver therapies locally at the disease site, whether the therapies are based on chemical compounds (including drugs and radiotherapeutics), genes, devices (including stents), cells, sound waves (HIFU) or temperature fluctuations (hyper- and hypothermia).
But a new generation of gene chips — devices that test the DNA at specific sites along the genome — can assess 500,000 of the genome's 3 billion units at a time.
These resultant TPP-inducible gene regulation devices showed obvious ligand dose-dependency and excellent specificity.
These results can be used for the rational design of dendrimer-based gene delivery devices.
PAMAM dendrimers, which are highly branched polymers with low polydispersity and high functionality, provide an ideal architecture for construction of effective drug carriers, gene transfer devices and imaging of biological systems.
The findings of this study provide better understanding of the binding strength between proteins and CNTs, and therefore have potential applications in both scientific research and in industry for controlling CNT self-assembly, designing bio-functionalized CNTs as biosensors, and drug and gene delivery devices.
A widely adopted strategy to engineer RNA gene regulatory devices exploits a self-cleaving ribozyme fused to an RNA aptamer (i.e., aptazyme) that serves as a chemical sensor.
For example, approximately 60 small molecule-binding RNA aptamers have been selected and characterized in vitro, yet theophylline overwhelmingly remains the sensing component used for in vivo engineered RNA-based gene regulatory devices.
Page B1 PORTABLE DNA SEQUENCER A British company said that by the end of the year it would begin selling a disposable gene sequencing device that is the size of a USB memory stick and plugs into a laptop computer to deliver its results.
A British company said on Friday that by the end of the year it would begin selling a disposable gene sequencing device that is the size of a USB memory stick and plugs into a laptop computer to deliver its results.
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