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This identified a one gene classifier, which classifies 99% of samples correctly in leave-one-out-crossvalidation (loocv).
Furthermore, we found WT1, a gene described as favorable for survival in MSKCC gene classifier, down-regulated in our list.
Consistent with previously published results, we found up-regulated some genes associated to poor survival and included in different prognostic classifiers, such as BTG2 (Karmanos gene classifier and MSKCC gene classifier) [13], [17], BIRC5 and KIF4A (Karmanos gene classifier), or SEPT9 (Brigham list) [15].
Previously, we identified a candidate progression-related gene classifier that had strong predictive value in terms of disease outcomes in NMIBC [13].
Here we have assessed the ability of a proposed 44 gene classifier [8] to discriminate between CFS patients and healthy control individuals.
Recently, we reported the identification of a progression-related gene classifier that had strong predictive value in terms of disease outcomes in NMIBC [13].
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The multivariate Cox regression analysis showed that the associations between the three gene classifiers and survival were much poorer than the 23-gene classifier.
To align with the original reports, we divided patients into three (for 35-gene classifier), four (for 44-gene classifier), and two (for 47-gene classifier) groups accordingly.
Alike the 23-gene classifier, the 6-gene clasignificantlyficantly discriminated patients into two survival groups in all the cohorts assessed, while the 11-gene classifier did not work well in two GBM cohorts (UCLA and CMBC).
Moreover, a 41-gene classifier based on expression signature can identify TAA patients with high accuracy.
A 41-gene classifier was identified based on its consistency in classification accuracy (Figure S1).
Related(20)
cell classifier
gender classifier
population classifier
gm classifier
sequence classifier
protein classifier
blood classifier
cancer classifier
type classifier
genie classifier
discomfort classifier
other classifier
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particular classifier
gene flow
gene inheritance
gene identification
gene splicing
gene pool
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