Exact(13)
IS performed some gene characterisation.
Representative isolates underwent ESBL gene characterisation and molecular typing.
Mutagenised plant populations are one such resource that facilitate gene characterisation.
Gene characterisation is enriched with information about the related Single Nucleotide Polymorphisms (SNPs), downloaded from dbSNP [ 10].
Assessing the temporal and spatial expression patterns of a gene by linking its regulatory regions to reporter genes is also a central component of gene characterisation.
Although the system and plasmid vectors described here were developed for applications in plants, the general approach is broadly applicable to gene characterisation studies in many biological systems.
Similar(47)
In this study, we chose the RNF11 gene for characterisation of its protein expression and mechanisms of action in normal and cancer cells because it was isolated from a tumour cell-enriched cDNA library, is unique, and contains modular domains and motifs known to interact with other proteins involved in oncogenesis.
Linkage mapping permits the location of genes controlling traits of importance to chromosomes through their association with molecular markers and thus, represents a powerful tool for the positional cloning of major genes, the characterisation of quantitative trait loci (QTL), and the anchoring and ordering of contigs and scaffolds of both physical maps and genome sequence assemblies.
Recent insights into their molecular pathogenesis with identification of susceptibility genes and characterisation of new proteins and pathways have led to improved diagnosis and development of rational therapies and have shed fascinating new light on aspects of the innate immune system.
To aid in immune gene identification and characterisation we have produced transcriptomes for Tasmanian devil lymph and spleen.
Unlike these single gene approaches, our characterisation of the phage head-neck-tail module is not hindered when one of the genes is particularly divergent, and this gene can even be detected, provided its genome position is canonical.
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