Only the total incidence of fever after the first vaccination was significantly different between the two groups (31/102 [30.4%], KD-287; 15/102 [14.7%], JEV-GCC, p = 0.012).
Radiological score (Kellgren and Lawrence summarized score for hands) after 1 year showed a reduced progression compared to the baseline in the hand osteoarthritis group, especially after GCC treatment (P < 0.05).
In total, 52 SAEs were reported: 23 occurred in 17 children in the KD-287 group and 29 occurred in 23 children in the JEV-GCC group (p = 0.373, Table 3).
When all migraine patients (without grouping) were compared with the control group, there were significant differences on all parameters: RNFL thickness, GCC thickness and CT (p < 0.05).
As shown in Figure 5, identifying as a democrat is positively correlated with GCC importance (r = 0.113, P <0.01), while identifying as a republican is negatively correlated with GCC importance (r = −0.11, P <0.05).
Nevertheless, we observed a better association between PSD, which indicates the severity of the disease, and RNFL (R = 0.1487, P = 0.0184) than GCC (R = 0.07782, P = 0.0945).
Species confirmation was performed using PCR amplification of the thermonuclease (nuc) gene with the primers; P-1: 5′ GCG ATT GAT GGT GAT ACG GTT 3′; P-2: 5′ AGC CAA GCC TTG ACG AAC TAA AGC 3′ as described previously [ 20].
We defined the p value using the fraction of GCC node numbers (GCC density) under random conditions, which was greater than the actual GCC fraction (GCC density).
Average GCC total (GCC av. Total), superior (GCC av. sup).
