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The phrase "gave up on" is correct and usable in written English.
You can use this phrase to refer to someone who has stopped trying or attempting to do something due to discouragement or despair. For example, "After she failed the exam, she gave up on her dream of becoming a doctor."
Exact(57)
They gave up on that one.
They gave up on the town after one week.
We gave up on sleep.
She gave up on justice.
"They never gave up on me".
"So I gave up on that".
Barcelona never gave up on him.
She gave up on that hospital.
That you gave up on us.
She never gave up on this task.
Similar(1)
"At one point, people gave up [on President Morsi].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com