The combination treatment with tamoxifen and taxanes gave an antagonistic effect at low concentrations, but an additive effect at high concentrations.
Using an effect-multiplication method to construct contour plots, the authors observed apparent synergisms with E2 and bisphenol A, whereas the remaining eight binary combinations gave additive, antagonistic, or weakly synergistic effects.
Vicente Rangel and Ramón Cabrera, known as the Big Flowerpot, are not private detectives, but they might as well be, given their antagonistic relationship with their fellow police officers and their inability to trust anyone else whose paths they cross.
However, the road to getting a share of concessions — famously the most profitable part of the business — will be a bumpy one, especially given the antagonistic stance MoviePass has taken with industry leaders like AMC.
Given the antagonistic effects on TCR signaling, CTLA4 engagement would be expected to inhibit this pathway, which has been demonstrated by some groups [22], [23].
Nevertheless, given mtr1p antagonistic function to mal3p, we examined mal3p dynamics in wild-type and mtr1Δ cells.
This would lead to an over-expression of this histone variant which, given its antagonistic relationship with DNA methylation, could in turn exacerbate the global DNA hypomethylation [ 12].
Given their antagonistic effects on the floral transition, the co-directionality of EDM2 and WNK8-dependent transcriptome changes seems counter-intuitive.
Since excess cholesterol or its removal determines the balance between either promoting or inhibiting angiogenesis, this balance may arguably be regulated by LXRs given their antagonistic actions on increasing HDL cholesterol [ 113] and stimulating cholesterol efflux via the RCT [ 94].
Given the antagonistic roles of NMDA and AMPA receptors for enabling reverberatory activity during WM [ 8], where NMDA to AMPA ratios have been proposed to be crucial, we focused on parameter estimates related to these receptor types.
