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This results in striatal sensorimotor gating deficits.
Future studies should investigate if gating deficits affect the distractibility of the same specific cognitive functions in patients with schizophrenia.
Patients demonstrated no impairment in SI gating, but a robust gating deficit in SII, supporting the presence of cross modal gating deficits in schizophrenia.
Moreover, administration of either dopamine D2 antagonists or mood stabilizers can partially reverse the sensorimotor gating deficits.
The major findings of the present study are that fractionated ionizing irradiation to the adult male rat brain causes schizophrenia-relevant abnormal behaviors (e.g., methamphetamine-induced hyperactivity, sensory motor gating deficits, social interaction deficits, and working memory deficits) at three months after the irradiation.
These mice have a reduced brain size, sensory gating deficits, social interaction deficits and cognitive impairments.
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P50 sensory gating deficit has repeatedly been demonstrated in schizophrenia.
Sensory gating deficit, as reflected by P50 suppression, has been demonstrated in schizophrenia.
The Sensory Gating Inventory (SGI) is an instrument investigating daily experiences of sensory gating deficit developed for English speaking schizophrenia patients.
The current study was designed to investigate the role of COMT Val108/158Met polymorphism in development, sensory gating deficit, and symptoms of schizophrenia in Han Chinese population.
All these psychiatric disorders displayed sensorimotor gating deficit (18).
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