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As we only gathered dose data on non-prescription analgesic, we could not determine if the combined total acetaminophen dose of the non-prescription analgesic product and prescription product exceeded the maximum recommended dose of acetaminophen in these three patients.
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Data gathered from dose escalation protocols for the treatment of prostate cancers conducted in the past 10 years have shown that rectal toxicity can be controlled by the use of careful conformal techniques.
All patient-reported outcomes were gathered pre-dose in the morning.
Accordingly, consideration of a study design other than the standard "3 + 3 design" in order to gather useful dose escalation-related information is also recommended in cancer peptide vaccine clinical studies.
A history of the patient's statin use was gathered, including the dose, duration and type of statin that was used.
Detailed analysis of the finger-stick samples gathered during the multiple dose phase showed a strictly proportional response to dose.
More specific for the study on rectal cancer, we can conclude from Table 2 that data gathered after an initial dose of cetuximab are more informative for prediction of therapy response than data gathered before the start of the therapy.
The biggest drawback of the PK/PD analysis in these studies is that the accuracy of the PK/exposure covariates relies entirely on the accuracy of the patient-reported dosing information gathered at each visit.
Follow-up surveys were completed at least 60 days after the date of parotitis onset for the household mumps index case-patient; information gathered included any MMR doses received by family members since the baseline interview and whether mumps developed in any household members.
Over the past decade, Sanberg and others had gathered anecdotal evidence that low doses of nicotine from patches or gum improve the tic-calming potential of other drugs, an effect also seen in rats.
There were substantial changes in apparent peripheral volume of distribution (V3/F) (from 84.3 l to 254 l) and Q/F (from 15.0 l to 19.1 l/h) due to an improved estimation achieved with the extra information gathered from the once-daily dosing.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com