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Conversely, anionic liposomes stabilized by positively charged gold nanoparticles are highly stable in gastric acid, but capable of fusing with bacteria at physiological pH, making them suitable to treat gastric pathogens such as Helicobacter pylori.
Frequent horizontal genetic exchange among groups would prevent speciation, or if it occurs after the speciation event, would lead to a 'despeciation' process, as has been proposed recently for the gastric pathogens Campylobacter jejuni and Campylobacter coli [ 57].
In this study, a detailed comparative genomic analysis between the human strain H. bizzozeronii CIII-1 and H. pylori showed important differences between these two human gastric pathogens, providing new insights into the comprehension of the biology of gastric Helicobacter species.
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Tombola, F. et al. Plant polyphenols inhibit VacA, a toxin secreted by the gastric pathogen Helicobacter pylori.
Bury-Moné, S. et al. Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori.
The gastric pathogen Helicobacter pylori interacts intimately with the gastric mucosa to avoid the microbicidal acid in the stomach lumen.
The gastric pathogen Helicobacter pylori relies on nickel-containing urease and hydrogenase enzymes in order to colonize the host.
The crystal structure of the dUTPase from the important gastric pathogen Campylobacter jejuni has been solved at 1.65 Å spacing.
The type IV secretion system (T4SS) protein CagL of the gastric pathogen Helicobacter pylori also contains an RGD motif.
Many of out studies focus on the gastric pathogen Helicobacter pylori, but we have also expanded our investigations to include the intestinal pathogens Listeria monocytogenes and Salmonella enterica, and the skin pathogen and colonizer Staphylococcus aureus.
We have recently found that the gastric pathogen Helicobacter pylori can activate gastric stem cells and increase epithelial turnover, while Wnt signalling is known to be important for stem cell identity and epithelial regeneration in several tissues.
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