Sentence examples for gas consensus from inspiring English sources
After 12 h of recovery, cells were co-transfected with pRL-CMV encoding Renilla luciferase (Promega, Madison, WI, USA) and either a firefly luciferase promoter-reporter construct containing three GAS consensus sequences (GAS reporter LR0075, Panomics, Fremont, CA, USA) or four ISRE consensus sequences (ISRE reporter LR0040).
A sequence motif closely resembling the GAS consensus is associated with large parts of the observed ChIP-seq signal.
Allowing one mismatch in the GAS consensus raises its frequency to 95% within 100bp to the determined binding sites in our set.
Comparing equally sized samples of all sets, a significant increase in the average content of GAS consensus sequences precisely at the position of the inferred STAT1 binding sites is consistently observed for all sets (Fig. 1, background content at distant positions <5%).
Upon its phosphorylation, STAT1 homo-dimerizes, and is transported into the nucleus where it binds to the gamma activated sequence (GAS; consensus: TTCNNNGAA [ 5]) to activate the expression of IFN-γ-responsive genes [ 6].
These STAT proteins translocate to the nucleus, where STAT1 STAT1 homodimers bind to gamma-activated sequence (GAS) sites (consensus sequence TTCNNNGAA) in gene promoters and activate transcription.
So far, none are after oil or natural gas, and the consensus is that there is "unlikely to be any drilling for oil and gas beyond national jurisdiction in the near future," Mr. Cook said in an e-mail.
In addition to better communications, international pressure, grid reliability and concern with the stability in natural gas prices, the consensus was that now, more than ever, nuclear energy policy will be forged at the grassroots level of the States with impetus from the new EPA carbon rules.
These scores were discussed in the multidisciplinary meeting, without the patients/caregivers, and a consensus GAS score was determined.
Most STATs bind to consensus GAS sites, TTCNmGAA, where m = 4 for STAT6 and m = 3 for the optimal binding of all other STATs [ 41, 42].
But the animals have also become a focal point for some elected officials and scientists who reject the need for cuts in the heat-trapping greenhouse gases, despite broad scientific consensus linking the gases to warming since 1950.
