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Two possible sensors for the decreasing gap on the lagging strand have been suggested.
Downstream re-priming of lagging-strand synthesis after blockage leaves a gap on the lagging strand, which can be repaired by recombination [ 10].
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Top-down fiscal policy measures: fixed effect panel instrumental variables (the fiscal policy variable is instrumented with its own lag, the lagged output gap, and the lagged government debt/GDP ratio).
Consistent with previous measurements performed on other DNA ligases (Pascal et al, 2004), we confirmed that S. solfataricus Lig1, while demonstrating robust DNA ligase activity, is unable to ligate an RNA-containing nick intermediate, which would arise as a result of PolB1 gap filling on our lagging strand substrate.
DNA adducts that block progression of the replicative polymerases result in ssDNA gaps on both lagging and leading strands, which can be acted on by TLS polymerases or by recombination.
Lagging with the lagging.
Gap on The Forbes 500s.
Clean the air gap on the magnet.
The closing of that gap is lagging in the mining industry, if not by far.
Despite a narrowing pay gap, the UK still lags behind on women's earnings.
Each polymerase also has its own function in the cell, such as acting on the leading or lagging strand, gap filling and synthesizing mitochondrial DNA (mtDNA).
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