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"I thought instead of doing some kind of gala type of thing, I'd rather do something I haven't done before in L.A. I've only conducted the piece twice before, and it's not something you want to conduct too many times in a lifetime". In between those engagements, the maestro plans to celebrate his 50th birthday in June and spend time composing at his house in Finland.
Furthermore it is very likely that the GALA type III effectors participate in virulence through their action in plant cells as the adaptors in SCF-type E3-ubiquitine ligases [4], [26].
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The danger of such gala-type events is that they become collections of showy party pieces.
Within a minute or two, however, this atmosphere is dissipated by the cheery gala-type antics of "Grazioso".
It has been shown that GALA are type III effectors required for virulence of R. solanacearum on three different plants, namely Arabidopsis, Tomato and Medicago truncatula.
Using the generalized profile technique [7], a sensitive method for sequence database searches, we found the GALA-LRR type of repeats in about 40 proteins including proteins of the cucurbit crops pathogenic β-proteobacterium Acidovorax avenae subsp. Citrulli, the human pathogen, and γ-proteobacterium Legionella pneumophila [8], as well as in the aquatic planctomycete bacterium Gemmata sp. Wal 1.
The options are staggering, with the potential for turning an ordinary lawn party into a Julia Child-type gala celebration.
The most diagnostic product was a disaccharide conjugate of the type pAMAC·UA-GalA (UA=unspecified uronic acid), whose UA-GalA bond was Driselase-resistant (product 2A).
It is tempting to propose that the selective pressure leading to an increase of variability on such residues could be the site of protein binding, relevant to the adaptor function of the F-box GALA proteins in the SCF-type E3 ubiquitin ligase.
Democratic Party officials have not staged the type of fund-raising gala here that the Republicans did in Philadelphia with a $10 million event headlined by Gov. George W. Bush.
The phytopathogenic bacterium Ralstonia solanacearum encodes type III effectors, called GALA proteins, which contain F-box and LRR domains.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com