Exact(2)
We show that PMM gains statistical power for hit detection due to parallel screening.
Because DNA methylation patterns at regulatory elements of the same type tend to respond similarly to changes in epigenomic cell states, our method gains statistical power by combining data on the level of genomic region sets.
Similar(58)
To avoid the variability of the slice selection and to gain statistical power, we used the entire striatum volume for the analysis.
While gaining statistical power by incorporating the ascertainment process in the full likelihood, this study has some clear limitations.
Every new screen could potentially gain statistical power by using the public resources.
The small effect size of disease traits requires a large sample size to gain statistical power.
To gain statistical power, a multivariate linear regression model was also applied and gave similar results (data not shown).
Most studies focus on cis-eQTLs [ 70] because trans-eQTLs require multiple testing to gain statistical power [ 71].
Thus, latitude in this context was used as a proxy for center to gain statistical power (continuous versus nominal scale).
Advanced versions of case-only study designs may be indicated to gain statistical power to study NSAID safety in children.
In this study, we aim to use the parallel screening structure in order to gain statistical power for hit selection in large-scale RNAi screens.
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