Generally, metal concentrations increase downstream.
if the data has 95% CI that overlaps with ERG gain → downstream effect, if the data has 95% CI that doesnot overlap with ERG gain → direct effect.
For ENI to get hold of more gas to feed into its European distribution network, Mr Scaroni says, it will have to gratify Gazprom's desire to gain direct "downstream" access to customers in Italy.
The CN gain on chromosome 7 is located in a chromosomal region where there are no annotated genes/miRNA/CpG islands, but the CN gain is downstream of a CpG island (CpG: 139) and upstream of the gene LOC643955 (function unknown).
Model results show that the Tukipo River is gaining, with increasing gain in the downstream direction.
Theoretically, two neighboring genes can switch from non-overlapping to overlapping through a 5' change (e.g., gaining a new upstream start signal), a 3' change (e.g., gaining a new downstream termination signal), or a combination of both mechanisms (Fig. 1).
Flood-driven recharge along predominantly losing reaches of the Bill Williams River (western Arizona, USA) later reemerges as baseflow in downstream gaining reaches, and the river's longest losing reach (Planet Valley) retains and releases the most flood recharge.
A MOR of 230 kb gain at 14q11.2 downstream of the DAD1 locus was observed in four tumors (20, 23, 27M, 28) which overlapped with partial or entire gains in five other tumors (1, 7, 25, 27P, 32).
However, our data on this mutation do not support a gain-of-function downstream of GTP-loaded Ras, neither could we observe any change in EGF-dependent Ras activation.
To complement these loss-of-function approaches, we used an activation-tagging screen to identify gain-of-function downstream components that may act in a redundant manner (Weigel et al. 2000).
