Exact(2)
If the protein gains a function, it is possible to be helpful but more likely it is harmful.
However, the evolutionary outcome may be different if the HEG or the intron gains a function other than endonuclease or splicing activity, respectively.
Similar(58)
Mutations can alter the structure of proteins that subsequently results in affecting their functions, either by gaining a function or losing one.
Some p53 missense mutations not only inhibit wild-type p53 activity but also gain a function that wild-type p53 does not have.
For the first time, the Institute gained a functioning clinic.
The fate of the duplicated genes might be loss of function, gaining a new function, or subfunctionalization [ 51].
Genetic gain is a function of selection intensity and genetic variance in addition to selection accuracy.
Lipid gain was a function of covariates in both species.
(a) Photoconductive gain as a function of applied bias.
Fig. 6 The gain as a function of laser dyes concentration.
Figure 7 Integrated PL, EL and EPL intensities and gain as a function of applied voltage.
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