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We hence decided to systematically compare complete periostin sequences and especially their C-terminal region across a range of phylogenetically diverse vertebrates in the hope of gaining clues to the functional role of the C-terminal region.
Understanding the compositional dynamics of genomes and their coding sequences is of great significance in gaining clues into molecular evolution and a large number of publically-available genome sequences have allowed us to quantitatively predict deviations of empirical data from their theoretical counterparts.
Understanding the molecular and cellular components of the intestinal barrier, and gaining clues into the processes by which mucosal disruption occurs in the pathogenesis of IBD and NEC, is no simple task, in part owing to the large variety of different types of cells (epithelial, immune, mesenchymal and endothelial) that must interact to maintain homeostasis.
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Whatever the case, astronomers hope that by learning how midsize black holes form, they can gain clues about the origin of the supermassive black holes, also a mystery.
The Pennsylvania authorities had recently revived the case, he said, and they were examining a tattoo on the man's forearm from a Marine Corps unit, and Mr. Nerney, a former Marine, was trying to gain clues to he man's identity through the tattoo.
Conversely, it's not easy for Turks to eavesdrop on or gain clues from other cultures.
Now, researchers have gained clues about the creatures' closest evolutionary kin by blasting fossils of one group of the animals with high-energy x-rays, which caused various elements in the fossils to fluoresce.
This could be the second significant case of coseismic slip partitioning after the 2001 Kokoxili, China, earthquake (King et al. 2005) and gives us a great opportunity to understand the mechanism of the slip partitioning and to gain clues for rupture dynamics and long-term fault development in a complex stress environment.
This methodology is employed to gain clues on the design of new fused thiadiazines with improved activity and selectivity on phosphodiesterase 7. Using the information achieved from the three CoMFA models, new structures have been designed in silico and their inhibitory activity on phosphodiesterase 7 was predicted.
Another way to gain clues about gene function is to monitor gene expression in response to stimuli or throughout development.
To gain clues to the roles of SET domain genes in these early developmental processes, we compared the expression levels of them in embryos at 0.75, 2 and 4 hpf with WISH analyses (Figure S6) and identified the highly expressed SET domain genes (Table 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com