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Dysfunction of p53-dependent pathways can allow tumour cells to evade the checkpoint controls and apoptosis, thereby gaining a selective advantage in attempting to overcome therapy (Lowe et al, 1993a).
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The pertactin-free whooping cough strain might have gained a selective advantage over those carrying the protein, he said.
In this model, slow-causing mutations gained a selective advantage in populations shifting from hunting-gathering to pastoralism/agriculture.
This principle is demonstrated by artificial-life simulations, like Avida [10], where computational tasks must be performed in order to gain a selective advantage.
In conclusion, we provided clear evidence for a correlation between the prevalence of slow acetylators in humans and the subsistence strategy adopted by the past populations in the last 10,000 years, suggesting that a slower rate of acetylation may have gained a selective advantage in populations shifting from foraging to pastoralism/agriculture in the Neolithic period.
Luca et al. [8] concluded that NAT2-altering variants may have gained a selective advantage in populations shifting from hunting-gathering to pastoralism/agriculture and proposed the diminished folate supply resulting from the nutritional shift as a possible cause of the fitness change.
Facultative intracellular bacteria invade host cells when they can gain a selective advantage in the host.
Cancer cells that successfully manage levels of ROS could therefore gain a selective advantage to expand a tumor.
Co-inoculation of equal numbers of both isolates would test if the tetracycline-resistant strain had gained a selective advantage over the erythromycin/lincomycin-resistant strain.
Resistant individuals would rapidly gain a selective advantage, leading to the fixation of the resistant spacer and its associated spacer inventory within the CRISPR locus.
As such, the spines would often be damaged, and individuals with larger numbers of epidermal secretory cells surrounding the spine could gain a selective advantage due to decreased healing time and a corresponding decreased chance of infection of exposed tissues.
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