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Results of this study demonstrated that 100% of subjects remained visually stable and 84.6% gained vision after switching to this dosing regimen.
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In "Poor Miss Finch, Collinss's description of the reactions of a person gaining vision for the first time after having been blind from birth (something extremely rare in his time, although it was discussed by thinkers like John Locke) has been praised for its psychological understanding.
One reason that Molyneux's problem could be posed in the first place is the dearth of human subjects who gain vision after extended congenital blindness.
A spokeswoman for Novartis said the company would continue to work with NICE and the Department of Health to "ensure appropriate patients are able to receive this very important treatment, which in clinical trials has been shown to double the likelihood of gaining vision and reduce the chance of losing vision by up to three-fold compared to laser treatment".
This indicates that patients who previously received vPDT could still gain vision when switched to ranibizumab.
At 6 months, 61.1% (22/36) showed stable or gaining vision, and 27.8% (10/36) gained three or more lines.
After a single session of triple therapy, 66.7% and 61.1% achieved stable or gaining vision 3 and 6 months, respectively.
The proportion of subjects maintaining or gaining vision from baseline to week 54 was nominally considered the primary efficacy endpoint.
In our study, visual improvement was achieved in those eyes previously classified in our schema as having the potential to gain vision with only CLET.
In optic neuritis, re-gaining vision is a genuine concern for the patient affected and hence may affect the person's adaptation of what they'd like to believe.
Finally, the "Western" theoretical education of Alexander and his young friends had not prepared them for gaining a clear vision of the realities of Russian life.
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