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For example, in vivo healed skin substitutes gained the expression of many native skin-expressed genes, including those associated with epidermal barrier and multiple categories of cell cell and cell basement membrane adhesion.
Furthermore, with the increase of implantation time, MDCs gradually lost their expression of myogenic molecules of MyoD and desmin and gained the expression of tenomodulin, a marker for tenocytes.
We recently demonstrated that when chromosomal region 11q13 was gained, the expression levels of several genes were elevated (Sugimoto et al, 2009).
Microarray analysis showed that DFOG cells lost expression of GC-specific marker genes, but gained the expression of osteogenic marker genes during dedifferentiation.
When cultured for up to 4 weeks in a cardiac differentiation-promoting medium, this same cell population gained the expression of a variety of paramount cardiac-specific proteins [ 55].
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This study was aimed to investigate whether pancreatic cancer expresses CX3-CR1-CL1, already gaining the expression of these chemotactic molecules in pre-invasive stages, and whether an association exists with PDAC features and outcome.
At present we do not prepare to gain the expression of analogues to (1.3) because it is hard to calculate the Fourier transform of.
After gaining the expression of GPC3, PLC-PRF-5 cells grew faster than the parental cells in serum-free medium.
After EMT, cells lose the expression of epithelial marker E-cadherin, but gain the expression of mesenchymal markers such as Vimentin, Snail, Slug, ZEB1 (zinc-finger E-box binding homeobox 1), and ZEB2 (Thiery et al, 2009).
During this so-called epithelial mesenchymal transition (EMT) cells lose epithelial markers, such as E-cadherin, and gain the expression of mesenchymal markers, such as N-cadherin and vimentin.
In addition, they gain the expression of regulatory molecules, frequently borrowed from the repertoire of natural killer (NK) cell receptors; these molecules include the killer immunoglobulin-like receptor (KIR) and the immunoglobulin-like transcript families, as well as natural-killer group 2, member D (NKG2D) [ 73, 74].
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