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The study was based on the experience gained in the analysis of approximately 5000 sputum samples in the past 10 years.
An important question is whether a data-driven approach can use knowledge gained in the analysis of one dataset to aid the analysis of other microarray data.
Metaphase chromosomes have generally been used for CGH and only limited additional information appears to have been gained in the analysis of childhood MGCTs by using 1 MB CGH arrays (Veltman et al, 2005).
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This might explain the power gained in the joint analysis.
Again, the conclusion is focused exclusively in the methodology used, not in the insight gained in the promoter analysis of Oct4, Sox2 and Nanog.
For example, in a French study, the ICER for biennial FIT was €8589 per life year saved (Hassan et al, 2011) compared with €1696 per QALY gained in this analysis.
The cost-utility is calculated as the cost per QALY gained in the base case analysis.
The transfer of knowledge and experience gained in the LL movement analysis to the UL domain is actually hindered by several sources of complexities, related to both the kinematic model and the evaluation protocol to be used.
The insights gained in the early process of the analysis of the qualitative data were broadened and validated by consultation of scientific literature and inspired our use of the theoretical framework.
The largest change in the cost per QALY gained in the one-way sensitivity analysis resulted when the cost of chemotherapy drugs was varied.
With Japanese distant recurrence risk data, the parameters whose change or uncertainty most altered the cost per QALY gained in the one-way sensitivity analysis were the: (1) cost of chemotherapy drugs, (2) cost of the 21-gene assay, and (3) patient's age at diagnosis.
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