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This is when the self-knowledge you gained in Step 1 pays off.
In the last (fourth) step, an optimisation is performed to identify the best (cost optimal) process using the experimental data gained in step three.
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The information about differences in spot positions that was gained in this step is reused later for image fusion and for the transfer of the consensus spot pattern.
The approach is also iterative, in revisions can take place in earlier steps based on information gained in later steps.
Using those individuals to impute BovineSNP50 genotypes to BovineHD genotypes may increase the accuracy gained in the first step, which would result in even higher accuracies when using the two-step approach than those obtained here.
Jones says, "I took a systematic approach by taking positions in my career in departments such as clinical R&D and project and portfolio management, so that I could maximize the opportunity to gain in-depth knowledge of every step of the R&D process".
A reviewer mentioned that if genes are lost or gained in a single step, that considering gaps individually dramatically over-emphasizes the number of evolutionary events.
The creation of expression profiles is critically informed (and improved) by the data about positional differences between gels that were gained in the first step.
Then, we clustered the genes gained in the previous step using the newly defined sample partitions (including all samples) to find the responsible gene subsets of high discriminating power.
Because of the low data compression gained in the assembly step and the small difference between contigs and reads mean length, bioinformatic processing of the 454 sequence data was performed on whole sets of unassembled reads.
The M&E process is iterative, where information gained in the latter steps can be used to go back and improve program responses in earlier steps.
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