Sentence examples for gained expression of from inspiring English sources

We found that airway epithelial cells gradually lost expression of junction proteins and gained expression of mesenchymal proteins, indicative of EMT.

Another possibility, supported by our previous work where human embryonic cells gained expression of pre-oligodendrocyte markers upon SMF exposure [8], was that the reduced proliferation we observed was a consequence of differentiation.

Transforming growth factor beta-1 (TGF-β1) levels increased in mouse airways while epithelial cells lost expression of E-cadherin and occludin and gained expression of the mesenchymal proteins vimentin, alpha-smooth muscle actin (α-SMA) and pro-collagen I.

Epithelial-to-mesenchymal transition (EMT) is an important mechanism during development and cancer progression whereby epithelial cells gain the capacity to migrate out of their context through down-regulation of epithelial markers, such as junction proteins and cytokeratins, and gained expression of mesenchymal proteins, such as vimentin and α-SMA [4], [5].

The same large differences remained at 24 months post-diagnosis, as it was evident that almost all CMV-specific cells had lost expression of CD27, CD28 and CD62L and gained expression of CD95, perforin and granzyme A, indicating that they were mature differentiated cells with the potential to kill virus infected cells [32], [35], [38].

Alternatively, how would J. coenia and A. io convergently have gained expression of N and Sal?

During the establishment of EMT, epithelial cells undergo a complex reprogramming of their cell proteome, in which proteins commonly expressed by epithelia (E-cadherin, cytokeratins) are lost, while cells gain expression of mesenchymal markers (N-cadherin, vimentin, α-smooth muscle actin (α-SMA), fibroblast specific protein-1 (FSP-1)).

Interestingly, the early EGF-induced ATMCs were also found to gain expression of the neural and progenitor cell marker nestin, which is transiently expressed in VSMCs progenitors of rat embryonic arteries.

In response to osteogenic induction conditions in culture, SCAP begin to down regulate their expression of CD24 while gaining expression of ALP (Figure 3B).

For example, mouse ES cells are capable of switching reversibly between Nanog positive and negative states, losing and gaining expression of a gene previously proposed as a key regulator of pluripotency [16].

A subpopulation of monocytes differentiates into fibrocytes by acquiring a fibroblast-like morphology, gaining expression of collagen I and CD34 while losing CD14 expression [ 2].