Hyperphosphorylated tau loses its ability to bind microtubules [ 34, 52, 53], thereby gaining the tendency to misfold.
ICV injections of the specific ERα antagonist MPP (Sun et al., 2002) to intact female rats induced weight gain and a tendency for food intake to increase in association with decreased BAT UCP1 expression and increased AMPK signaling in the VMH.
In Mo15MnBS31, Mo15MnCS31, and Mo15MnNS31, the peaks of the dielectric function all reflect the redshift phenomenon in which the value of the peaks in the high-energy region becomes gentle and small and the whole tendency gains no more changes.
If less than 50% of the connections were normal, then there was an increased tendency to gain weight (the probability to gain weight increased).
Whatever the reason for any one individual's tendency to gain weight, the only way to lose the weight is to eat less and exercise more.
Those of us who have a tendency to gain weight should consider ourselves lucky that the red light is so clearly visible.
But within the year the Sinatra tendency would gain the upper hand as Mack the Knife propelled him out of the high-school prom and into the supper club.
Other common symptoms are dry skin and hair, decreased perspiration, puffy eyes, cold intolerance, deepening of the voice, decreased appetite but a tendency to gain weight, constipation, and irregular menstrual periods and increased menstrual blood flow in women.
A similar situation exists with the definitions of oxidizing and reducing agents, which are defined respectively as species having a tendency to gain or lose electrons, even though one of these reactions never occurs alone and free electrons are never detected in solution (any more than free protons are).
Electromotive series, listing of chemical species (atoms, molecules, and ions) in the order of their tendency to gain or lose electrons (be reduced or oxidized, respectively), expressed in volts and measured with reference to the hydrogen electrode, which is taken as a standard and arbitrarily assigned the voltage of zero.
