"We don't know which parts are needed, but as we build the table we will gain functional information into how the pieces work".
We therefore implemented parallel transcriptomic and proteomic analysis to study filarial nematode tissue-specific transcriptional patterns in order to gain functional information.
To gain functional information about these proteins, BLASTP (http://www.ncbi.nlm.nih.gov/BLAST/) was used to search for homologous proteins against the NCBI non redundant (Nr) protein database.
To gain more structural and functional information on the actomyosin complexes, we have engineered chimera proteins carrying the entire Dictyostelium actin in the loop 2 sequence of the motor domain of Dictyostelium myosin II.
Hence, the combination of structural MRI and fMRI provides the possibility to gain morphologic information on the auditory system along with functional information on patients' ability to hear.
To gain further insights into the iron storage process of Mtb BfrB, the structure is analyzed with respect to available structural and functional information on representative members of the ferritin family.
We have found functional information on 13 of these sites.
However, there is very little functional information on BCL9.
The Ingenuity Pathways Analysis tool (Ingenuity Systems, www.ingenuity.com) was used to gain additional in silico functional information.
