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They lose muscle and gain fat.
Fat and support tissue becomes lost or moves down the face - we lose fat in our lips or cheeks, but gain fat under our eyelids,' he said.
"The group that doesn't gain fat in the liver as they get obese seems to avoid inflammation and maintain their metabolic health," said Dr. Jussi Naukkarinen, a research scientist specializing in internal medicine at the University of Helsinki.
"Girls gain fat, and in some cases there is a decrease in iron stores and hemoglobin level of the blood," said Dr. Oded Bar-Or, who is director of the Children's Exercise and Nutrition Center at McMaster University in Hamilton, Ontario, and a leading researcher in the field.
The phenomenon accounts for why many runners gain fat while training for a race.
Postmenopausal women are more susceptible to weight gain, fat redistribution and dyslipidemia, all major hallmarks of metabolic syndrome associated with increased NAFLD risk.
Similar(19)
The rationale to switch all mice to a LF diet at an early age is based on the fact that even with standard chow feeding, C57Bl/6 mice quickly gain fat-mass at variable rates, which may mask effects of AOiGHD.
But fitness offered some protection to those who gained fat.
Those at greatest risk for these health problems were, unsurprisingly, those who'd both lost fitness and gained fat.
Those who had gained fat also had spontaneously, without any intention or desire to do so, decreased their everyday activity levels.
One study of overweight women in Arizona found that while they were all more aerobically fit at the end of 12 weeks of supervised exercise, almost 70% had gained fat.
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